HIGHLIGHTS
- who: Jan Fiedler and Thomas Thum from the Pittsburgh, United States have published the research work: Bioinformatics-Based Transcription Factor Profiling in Hypoxic Human Endothelial Cells Identify Pro-angiogenic Factors, in the Journal: (JOURNAL)
- what: SP1 and KLF5-Knockdown Mediated Differential Gene Expression After Hypoxia Next, the authors aimed to investigate the effect of TF modulation on hypoxia-induced endothelial gene transcription. This study reports the key contribution of endothelial TFs SP1 and KLF5 during human EC hypoxic gene response. The authors focus more on identifying major regulatory Frontiers in Cardiovascular Medicine | www.frontiersin.org . . .
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