Biological chemistry

HIGHLIGHTS

• who: ChristophPeter from the (UNIVERSITY) have published the research: Biological Chemistry, in the Journal: (JOURNAL)
• what: The authors show for the first time that is symmetrically dimethylated by within the RG-rich region in its C-terminus. The authors demonstrate that NF90 is recruited exclusively via the adapter protein RioK1 to the PRMT5-WD45 complex, where it is rapidly methylated in its C-terminal region at the RG-boxes. In this follow-up study, the authors show that NF90 is indeed a binding partner and a new substrate of PRMT5 in_vitro and in_vivo. NF90 is . . .
  

   

  

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