Biological chemistry

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  • who: Alexander W.Friedrich from the Very recently, Lopez-Alvarez and colleagues examined in our hospital (University Medical Center Groningen) the potential of the nuclease-activatable, and TT probe for the detection of Saureus directly from clinical blood culture samples (Lu00f3pez-u00c1lvarez et_al, ). The probe consists of an oligonucleotide comprising, u2032-O-methyl modified uridines flanking a pair of unmodified deoxythymidines, which is coupled to fluorescein amidite on the, u2032-end and the ZEN and Iowa Black RQ quenchers on the, u2032-end (Lu00f3pez-u00c1lvarez et_al, ). Activation of this probe by MNase cleavage leads to the emission . . .

     

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