Biological, pharmacological and immunological activities of novel 6-amino-acid-substituted 14-alkoxy- n -methylmorphinans

HIGHLIGHTS

  • who: Guerrieri et_al BMC Pharmacology and colleagues from the (UNIVERSITY) have published the research work: Biological, pharmacological and immunological activities of novel 6-amino-acid-substituted 14-alkoxy- N -methylmorphinans, in the Journal: (JOURNAL)
  • what: Novel MOP agonists acting in the periphery with combined immunosuppressive and analgesic properties may provide a new approach for the treatment of IBD.

SUMMARY

    Of the three opioid receptors, μ (MOP), δ (DOP) and_(KOP), the MOP type is the most involved in the action of opioids in the gut. Experimental studies on models of intestinal inflammation and . . .

     

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