Biologically relevant small variations of intra-cellular ph can have signi fi cant effect on stability of protein – dna complexes, including the nucleosome

HIGHLIGHTS

  • who: April and collaborators from the , BIT University, China have published the research work: Biologically relevant small variations of intra-cellular pH can have signi fi cant effect on stability of protein - DNA complexes, including the nucleosome, in the Journal: (JOURNAL)
  • what: This work is intended to fill the gap, focusing on quantitative predictions suggestive of possible biological relevance. The aim of this work is to determine whether biologically relevant variations of pH of the environment may cause potentially biologically relevant changes in thermodynamic stability of protein - (nucleic_acid) complexes relevant to chromatin function. Note that . . .

     

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