Biomarkers in neurodegenerative diseases: proteomics spotlight on als and parkinson’s disease

HIGHLIGHTS

  • who: Rekha Raghunathan et al. from the New York, NY, USA have published the paper: Biomarkers in Neurodegenerative Diseases: Proteomics Spotlight on ALS and Parkinsonu2019s Disease, in the Journal: (JOURNAL)
  • what: The authors compare relative and absolute quantitative proteomic approaches in key biomarker studies in ALS and PD and discuss recent technological advancements which may identify suitable biomarkers for the early-diagnosis treatment efficacy of these diseases. Using both discovery and targeted proteomics approaches to validate markers in an independent cohort, this study provides a comprehensive and validated approach in identifying biomarkers.
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