HIGHLIGHTS
SUMMARY
The interaction between APO E4 and CSF Ng was investigated in a population of AD and MCI patients, and the authors found higher levels of the protein in MCI carrying APOE e4(+) than APOE e4(-), suggesting an effect of APOE in determining the levels of CSF Ng in the early stages of AD. Janelidzed and colleagues showed that the diagnostic performance of the Aβ-42/Ng ratio did not differ from that of the Aβ 42/40 ratio, when they compared AD to non-AD dementias or cognitively stable MCI from MCI that converted . . .
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