Biomaterial-mediated protein expression induced by peptide-mrna nanoparticles embedded in lyophilized collagen scaffolds

HIGHLIGHTS

• who: Rik Oude Egberink and colleagues from the Department of Biochemistry, Radboud Institute for Molecular Life Sciences (RIMLS), Radboud University Medical Center, Geert Grooteplein, GA Nijmegen, The Netherlands have published the article: Biomaterial-Mediated Protein Expression Induced by Peptide-mRNA Nanoparticles Embedded in Lyophilized Collagen Scaffolds, in the Journal: Pharmaceutics 2022, 1619 of 28/07/2022
• what: Using fluorescently labeled mRNA, the authors demonstrate that peptide-mRNA nanoparticles are uniformly distributed throughout the scaffold. The authors demonstrate the incorporation of peptide-formulated mRNA into porous collagen scaffolds yielding nanoparticle-functionalized collagen-based biomaterials that can . . .
  

   

  

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