HIGHLIGHTS
- who: November et al. from the Kou00e7 University, Turkey have published the Article: Biomaterials and bioengineering to guide tissue morphogenesis in epithelial organoids, in the Journal: (JOURNAL)
- future: Elaborate and systematic studies are needed biochemical mechanical and functional characteristics of human organs and better understand organogenesis.
SUMMARY
Dysregulation of ECM remodeling including composition, structure, orientation, and stiffness leads to aberrant organ morphogenesis and pathological conditions, such as fibrosis and cancer (Tian et_al, 2013; Bonnans et_al, 2014). While α3(IV) and α 4(IV) chains are restricted on the top of the villus . . .
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