HIGHLIGHTS
- who: USER from the Lorenzo Casalino et al (2020) from the University of California emphasized the important structural role of Nglycans at sites , and , in adjusting the conformational dynamics of the spike`s receptor binding domain, which is responsible for ACEII receptor recognitionThey supported their notion by biolayer interferometry experiments, which revealed that deletion of the, glycans at sites , and , through N A and N A mutations considerably decreased binding to ACE II receptor because of the associated shift of spike`s receptor binding domain conformation toward the a down state. have published the research: Biomedical and . . .
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