Biomimetic cardiac tissue culture model (ctcm) to emulate cardiac physiology and pathophysiology ex vivo

HIGHLIGHTS

  • who: Jessica M. Miller from the Department University of Louisville, Louisville, USA have published the research: Biomimetic cardiac tissue culture model (CTCM) to emulate cardiac physiology and pathophysiology ex vivo, in the Journal: (JOURNAL) of 30/08/2022
  • what: In this study a CTCM device that can stimulate ultra-thin heart slices was developed and characterized. This study shows that mechanical stretches and humoral stimulation are essential to maintain cardiac tissue slices in culture.
  • future: Studies are needed to add multiplexity to the CTCM such as co-culture with immune cells circulating humoral . . .

     

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