Biophysical ambiguities prevent accurate genetic prediction

HIGHLIGHTS

  • who: Xianghua Li from the The Barcelona Institute have published the paper: Biophysical ambiguities prevent accurate genetic prediction, in the Journal: NATURE COMMUNICATIONS NATURE COMMUNICATIONS
  • what: The authors show that, for diverse biological systems, the answer to this question will often be no. Using gene regulation by the lambda repressor model, the authors show that, even for a very simple biophysical system, it is often impossible to predict what happens when two mutations are combined even if the authors have perfect measurements of their effects on a trait.
  • how: To better understand how . . .

     

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