Biotransformation of penindolone, an influenza a virus inhibitor

HIGHLIGHTS

  • who: Shuai Liu et al. from the Ocean University of China, Qingdao, China have published the article: Biotransformation of Penindolone, an Influenza A Virus Inhibitor, in the Journal: Molecules 2023, 28, 1479. of /2023/
  • what: The aim of this work was to reveal the metabolic route of PND in rats.

SUMMARY

    Although the anti-IAV activities and mechanism of PND, as well as its plasma pharmacokinetics in_vivo were explored, the disposition fate of PND remains unclear. In a previous study, several metabolites (oxidation and glucuronidation reactions) of PND were detected in . . .

     

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