Biphasic regulation of cftr expression by enac in epithelial cells: the involvement of ca -modulated camp production

HIGHLIGHTS

  • who: August and colleagues from the Leipzig, Germany have published the paper: Biphasic regulation of CFTR expression by ENaC in epithelial cells: The involvement of Ca -modulated cAMP production, in the Journal: (JOURNAL)
  • what: This study has demonstrated that CFTR functional expression in endometrial and airway epithelial_cells may be subject to a biphasic regulation by ENaC .
  • how: Showed that in all these ISK lines the addition of benzamil (10 u00b5M) induced a decrease in DiBAC4(3) intensity indicating Vm hyperpolarization consistent with the known role of active ENaC in endometrial epithelial_cells in mediating . . .

     

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