Bivariate genome-wide association meta-analysis of pediatric musculoskeletal traits reveals pleiotropic effects at the srebf1/tom1l2 locus

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  • who: Carolina Medina-Gomez from the MC University of Epidemiology, Erasmus Medical Center, Rotterdam GE, The Netherlands have published the research: Bivariate genome-wide association meta-analysis of pediatric musculoskeletal traits reveals pleiotropic effects at the SREBF1/TOM1L2 locus, in the Journal: NATURE COMMUNICATIONS NATURE COMMUNICATIONS
  • what: Although for most of these loci the association with TBLH-BMD is the dominant association responsible for their significance, the authors report in the 17p11.2 locus, a stronger association with TB-LM compared to TBLH-BMD. The authors show that this methodology may help discover previously unknown . . .

     

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