Blm and rmi1 alleviate rpa inhibition of topoiii a decatenase activity

HIGHLIGHTS

  • who: Jay Yang and collaborators from the Department of Biochemistry and Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, Ontario, Canada, Weatherall Institute of have published the Article: BLM and RMI1 Alleviate RPA Inhibition of TopoIII a Decatenase Activity, in the Journal: (JOURNAL) of July/20,/2012
  • what: The authors propose that topoisomerase IIIa and RPA compete to bind to single-stranded regions of catenanes. The authors investigated whether RPA modulates the second step of the dissolution reaction the decatenation by TopoIIIa. The authors propose a competitive binding model in which RPA . . .

     

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