HIGHLIGHTS
- who: Marie A. C. Depuydt from the DivisionLeiden University, Leiden, The Netherlands have published the research: Blockade of the BLT1-LTB4 axis does not affect mast cell migration towards advanced atherosclerotic lesions in LDLr-/- mice, in the Journal: Scientific Reports Scientific Reports
- what: The authors aimed to investigate whether inhibition of the BLT1-LTB4 axis via BLT1antagonism limits mast cell accumulation in advanced atherosclerosis and via this way prevent plaque instability. As the authors show here, these genes are also detected in the murine single-cell_RNA_sequencing d u00ad ata29, while protein expression of ALOX5 and . . .
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