Blockage of khsrp-nlrp3 by mcc950 can reverse the effect of manganese-induced neuroinflammation in n2a cells and rat brain

HIGHLIGHTS

  • who: Sharad Singh and collaborators from the School of Basic and Applied Sciences, Dayananda Sagar University, Bangalore, Karnataka, India have published the paper: Blockage of KHSRP-NLRP3 by MCC950 Can Reverse the Effect of Manganese-Induced Neuroinflammation in N2a Cells and Rat Brain, in the Journal: (JOURNAL)
  • what: Despite the work undertaken in this area, the detailed mechanism of manganese toxicity is poorly understood. The authors investigated the role of KHSRP in Mn-induced neurotoxicity and inflammation. The actual causes of neurodegenerative diseases are unknown; however, it is believed that the major reason is genetic . . .

     

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