Blockage of transient receptor potential vanilloid 4 inhibits brain edema in middle cerebral artery occlusion mice

HIGHLIGHTS

• who: Lei Chen from the Department of Physiology, Nanjing Medical University, Nanjing, China have published the research: Blockage of transient receptor potential vanilloid 4 inhibits brain edema in middle cerebral artery occlusion mice, in the Journal: (JOURNAL)
• what: The authors first examined whether blockage of TRPV4 could reduce brain edema in a mouse model of focal cerebral ischemia by using the middle cerebral artery occlusion (MCAO) and then explored the mechanism underlying TRPV4 action by examining the effect of TRPV4 blockage/activation on the expression and activity of MMP-2/9.
• future: In . . .
  

   

  

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