Blocking polyphosphate mobilization inhibits pho4 activation and virulence in the pathogen candida albicans

HIGHLIGHTS

• who: Yasmin Ahmed et al. from the WKronstad, University of British California Merced, Merced, California, USA have published the research work: Blocking Polyphosphate Mobilization Inhibits Pho4 Activation and Virulence in the Pathogen Candida albicans, in the Journal: (JOURNAL) of 13/07/2022
• what: The authors show that two polyphosphatases, Ppn1 and Ppx1, function redundantly to mobilize polyP stores in C. albicans. The authors also found that blocking polyP mobilization impairs activation of the PHO pathway, and this, to the best of the knowledge , is the first such report (Fig 8). As the authors show that . . .
  

   

  

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