Blocking the cxcl1-cxcr2 axis enhances the effects of doxorubicin in hcc by remodelling the tumour microenvironment via the nf-κb/il-1β/cxcl1 signalling pathway

HIGHLIGHTS

• who: Huiyong Zhao from the Patient specimens and tissue microarrays Fifty-one patients with liver cancer who underwent hepatectomy at The Second Hospital of Anhui Medical University (between , and, ) without antitumour treatment prior to surgery were enrolledWe collected their tumour tissues and paired adjacent tissues. Most of these patients have a history of hepatitis and cirrhosis. The diagnosis was confirmed by pathology. The participants involved in the study signed the informed consent. The research protocol was approved by The Second Hospital of Anhui Medical University Institutional Review Committee. Tissue microarrays (TMAs) of HCC samples from these patients . . .
  

   

  

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