Blocking tigit/cd155 signalling reverses cd8+ t cell exhaustion and enhances the antitumor activity in cervical cancer

HIGHLIGHTS

  • who: Lu Liu from the One hundred thirteen peripheral blood samples were collected, including , from patients with cervical cancer, from patients with high-grade squamous intraepithelial lesion (HSIL), and , from subjects with a normal cervixIn addition, we collected , pairs of cervical cancer and adjacent tissues. All patients with cervical cancer included in this study underwent primary surgery. All samples were collected from the Qilu Hospital of Shandong University. The study was approved by Qilu Hospital`s ethics committee. Cell isolation have published the research: Blocking TIGIT/CD155 signalling reverses CD8+ T cell exhaustion and enhances the antitumor . . .

     

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