Blood-based dna methylation markers for lung cancer prediction

HIGHLIGHTS

• What: This study aimed to evaluate if it is possible to define a blood-­ based DNA methylation signature that improves risk assessment for lung cancer among individuals with a smoking history, either as a standalone marker or in combination with an established smoking history-­ based risk model. The authors also note that the study design does not readily allow the authors to establish an absolute risk model, which is a pre-­requisite for translation into a practical screening situation. This study design minimises the possibility that the CpG sites studied are affected by the presence of an . . .
  

   

  

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