HIGHLIGHTS
- who: Ruicheng Yang and collaborators from the State Key Laboratory of Agricultural Microbiology, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, China have published the research: Blood-Brain Barrier Integrity Damage in Bacterial Meningitis: The Underlying Link, Mechanisms, and Therapeutic Targets, in the Journal: (JOURNAL)
- what: The study has shown that macrophage migration inhibitory factor (MIF) was significantly upregulated in meningitic E. coli infected-hBMECs. The authors similarly showed that meningitic E. coli induces SNAI1 and that SNAI1 negatively regulates the junctional proteins ZO-1, Occludin, Claudin-5, and u03b2-catenin.
- future: At . . .
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