Blood brain-derived neurotrophic factor (bdnf) and major depression: do we have a translational perspective?

HIGHLIGHTS

  • who: Ivan Aprahamian from the Community Health, University of Milan, Milan, Italy, IRCCS Fondazione Don Carlo Gnocchi, ONLUS, Milan, Italy have published the article: Blood Brain-Derived Neurotrophic Factor (BDNF) and Major Depression: Do We Have a Translational Perspective?, in the Journal: (JOURNAL)
  • what: Experimental and clinical evidence points to both blood BDNF levels (serum or plasma) and the BDNF Val66Met polymorphism as being linked to MDD pathophysiology and treatment response.
  • how: Six studies were evaluated in a recent meta-analysis with conflicting results regarding the effect of physical exercise on resting concentrations . . .

     

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