Blood culture-pcr to optimise typhoid fever diagnosis after controlled human infection identifies frequent asymptomatic cases and evidence of primary bacteraemia

HIGHLIGHTS

  • who: Thomas C. Darton from the University of Oxford, Oxford, United Kingdom have published the Article: Blood culture-PCR to optimise typhoid fever diagnosis after controlled human infection identifies frequent asymptomatic cases and evidence of primary bacteraemia, in the Journal: (JOURNAL)
  • what: While all blood culture and PCR data were generated prospectively during the study, only blood culture results were used to make clinical management decisions. The authors have previously described the first culture-PCR assay for detecting S. Typhi in the modern era ; here, the authors demonstrate the performance of this method, specifically designed . . .

     

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