Blood-tumor barrier opening by mri-guided transcranial focused ultrasound in a preclinical breast cancer brain metastasis model improves efficacy of combinatorial chemotherapy

HIGHLIGHTS

  • who: Tasneem A. Arsiwala and colleagues from the India University of Florida, United States have published the research: Blood-tumor barrier opening by MRI-guided transcranial focused ultrasound in a preclinical breast cancer brain metastasis model improves efficacy of combinatorial chemotherapy, in the Journal: (JOURNAL)
  • what: The authors demonstrate that a clinically relevant LiFUS regimen significantly increases the therapeutic efficacy of Pax and Doxil in a preclinical model of TNBC brain metastasis through BTB disruption. While the study demonstrates increased therapeutic efficacy of combinatorial chemotherapy with LiFUS, there are a few limitations.
  • how . . .

     

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