Bmp receptor inhibition enhances tissue repair in endoglin heterozygous mice

HIGHLIGHTS

  • who: Wineke Bakker and collaborators from the Department of Cell and Chemical Biology, Leiden University Medical Center have published the paper: BMP Receptor Inhibition Enhances Tissue Repair in Endoglin Heterozygous Mice, in the Journal: (JOURNAL) of 18/02/2021
  • what: The aim of this study was to elucidate the effect of endoglin heterozygosity on M1 and M2 macrophages during the different phases of cardiac wound healing and vascular recovery. The authors showed that monocytes depend on the expression of endoglin to be able to differentiate from an inflammatory M1 macrophage towards a reparative M2 macrophage . . .

     

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