Bone disease in multiple myeloma: biologic and clinical implications

HIGHLIGHTS

• who: Zachary S. Bernstein and collaborators from the Center for Multiple Myeloma, Massachusetts General Hospital Cancer Center, Boston, MA, USA have published the Article: Bone Disease in Multiple Myeloma: Biologic and Clinical Implications, in the Journal: Cells 2022, 11, x FOR PEER REVIEW of /2022/
• how: Showed that MM cells can directly inhibit OB proliferation and even make OBs more prone to apoptosis .
• future: At this point it is also recommended that discontinuation of denosumab is avoided due to data showing a rebound of elevated resorptive activity characterized by osteoclastogenesis rapid decline in . . .
  

   

  

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