HIGHLIGHTS
- who: . and colleagues from the University of Naples Federico II, Italy have published the research work: Bone marrow mesenchymal stromal cell-derived small extracellular vesicles: A novel therapeutic agent in ischemic heart diseases, in the Journal: (JOURNAL)
- what: In the study, the authors showed that miR-210 carried by sEVs could target the AIFM-3/AKT/p53 pathway (Cheng et_al, 2020), which may be the core mechanism of protective effects, suggesting that the miRNAs carried by sEVs are the main reasons for its beneficial effects.
- how: Interestingly preclinical and clinical data indicated that . . .
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