Bordetella spp. utilize the type 3 secretion system to manipulate the vip/vpac2 signaling and promote colonization and persistence of the three classical bordetella in the lower respiratory tract

HIGHLIGHTS

• who: Nicholas J. First from the University of Leeds, United Kingdom have published the article: Bordetella spp. utilize the type 3 secretion system to manipulate the VIP/VPAC2 signaling and promote colonization and persistence of the three classical Bordetella in the lower respiratory tract, in the Journal: (JOURNAL)
• what: Using the B. bronchiseptica murine model the authors determine the suitability of VPAC2 antagonists as possible therapy for Bordetella spp. infections. The authors wanted to investigate if blocking this signaling cascade would promote clearance of Bordetella spp.
• how: All animal experiments were carried out . . .
  

   

  

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