Botulinum neurotoxin a ameliorates depressive-like behavior in a reserpine-induced parkinson⠒s disease mouse model via suppressing hippocampal microglial engulfment and neuroinflammation

HIGHLIGHTS

• who: Yang Li from the Animals Adult (approximately , g, weeks old) male ICR mice were purchased from the Shanghai SLAC Laboratory Animal Co [, ]Ltd. (Shanghai, China). Animals were fed in an environment with a pressure ventilation system, an ambient temperature maintained at , u00b1 , u00b0C, and a relative humidity maintained at, %-70%. Mice were housed in a, h/12-h light/dark cycle (8:00-20:00) and provided with standard mouse chow and water ad libitum. The behavioral tests were mainly carried out in the experimental animal operating room from, :, a.m. to, :, p.m., and the . . .
  

   

  

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