Botulinum neurotoxin chimeras suppress stimulation by capsaicin of rat trigeminal sensory neurons in vivo and in vitro

HIGHLIGHTS

  • who: Caren Antoniazzi and collaborators from the International Centre for Neurotherapeutics, Dublin City University, Collins , Dublin, Ireland have published the article: Botulinum Neurotoxin Chimeras Suppress Stimulation by Capsaicin of Rat Trigeminal Sensory Neurons In Vivo and In Vitro, in the Journal: Toxins 2022, 116 of 13/Dec/2021
  • what: LC/E-BoNT/A significantly reduced capsaicin-induced acute nociception over several days, after unilateral administration into a whisker pad, without altering spontaneous behavior or locomotor performance in control rats.

SUMMARY

    Iations. This consists of LC.HN /E (LC together with an . . .

     

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