HIGHLIGHTS
- who: Kyle M. Reid from the Department of Biochemistry, University of Cambridge, Cambridge, United Kingdom have published the research work: Brain Cells Release Calreticulin That Attracts and Activates Microglia, and Inhibits Amyloid Beta Aggregation and Neurotoxicity, in the Journal: (JOURNAL)
- what: It is not known whether extracellular calreticulin can recruit and activate microglia, so the authors aimed to test this here.
SUMMARY
Calreticulin is a highly-conserved chaperone that is constitutively expressed in virtually all mammalian cell-types. During conditions of apoptosis or ER stress, calreticulin can be translocated to the . . .
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