HIGHLIGHTS
SUMMARY
A more comprehensive examination of abnormalities in brain morphometry in MUD individuals using surface-based morphometry (SBM), including CT, surface area (SA), cortical volume (CV), and local gyrification index (LGI), may advance the understanding of the effects of METH on the brain. The authors hypothesized that the brain morphometric alterations would be observed in the PFC, ACC, and NAcc which are the key brain regions in the mesocorticolimbic system and that some of the abnormalities would be related to affective symptoms in the MUDs during abstinence. Associations between brain morphometric abnormalities and affective symptoms . . .
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