HIGHLIGHTS
- who: Kun Zang and collaborators from the The Key Laboratory of Molecular Medicine, Ministry of Education, Fudan University, PR China, Department of Biochemistry and Molecular have published the research work: Brd2 Inhibits Adipogenesis via the ERK1/2 Signaling Pathway in 3T3-L1 Adipocytes, in the Journal: PLOS ONE | www.plosone.org of October/23,/2013
- what: The authors show that Brd2 over-expression in preadipocytes inhibits their differentiation into adipocytes while Brd2 knockdown promotes adipogenic differentiation in vitro and forces cells to undergo adipogenesis independent of the MDI (methyisobutylxanthane dexamethasone and insulin) induction. The authors . . .
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