Breaking the mucin barrier: a new affinity chromatography-mass spectrometry approach to unveil potential cell markers and pathways altered in pseudomyxoma peritonei

HIGHLIGHTS

• What: As in other rare diseases, both the low incidence of PMP (3.2 cases per one million people/year) and the lack of molecular studies focused on this condition make it difficult to obtain a detailed description of its pathophysiology and thus to develop efficient, novel diagnostic, prognostic, or therapeutic strategies . This study provides a description of the first protocol available to isolate total protein from mucin obtained from soft and hard tumour samples, which will undoubtedly advance research in this field, as it allowed the authors to identify a potential tumour cell marker. The authors . . .
  

   

  

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