Bridging the gap between non-targeted stable isotope labeling and metabolic flux analysis

HIGHLIGHTS

  • who: Daniel Weindl from the (UNIVERSITY) have published the research work: Bridging the gap between non-targeted stable isotope labeling and metabolic flux analysis, in the Journal: (JOURNAL)
  • what: The authors show how similarity-analysis of isotopic enrichment patterns can be used for pathway contextualization of unidentified compounds. As a similarity measure, the authors compare the Canberra distances of all pairwisely aligned MIDs. Whereas Nakayama et_al analyzed time-series data from a transient labeling experiment, the authors compare MIDs from only one single time-point. Only during the preparation of this manuscript, two independent studies . . .

     

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