Brief exposure of neuronal cells to levels of scfas observed in human systemic circulation impair lipid metabolism resulting in apoptosis

HIGHLIGHTS

  • who: Tiffany A. Fillier from the DepartmentMemorial University have published the paper: Brief exposure of neuronal cells to levels of SCFAs observed in human systemic circulation impair lipid metabolism resulting in apoptosis, in the Journal: Scientific Reports Scientific Reports
  • what: This study shows that the elevated levels of SCFAs reported in systemic circulation of patience during gut dysbiosis and other pathological conditions significantly altered neuronal cells and Long-Evans's rat brain lipidome, with the most noted alterations observed in mitochondrial specific lipids and PE plasmalogens. Based on the findings in this study, the authors . . .

     

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