Broad coverage of neutralization-resistant siv strains by second-generation siv-specific antibodies targeting the region involved in binding cd4

HIGHLIGHTS

  • who: Hugh C. Welles and colleagues from the Editor: Guido Silvestri, Emory University, UNITED have published the paper: Broad coverage of neutralization-resistant SIV strains by second-generation SIV-specific antibodies targeting the region involved in binding CD4, in the Journal: (JOURNAL) of June/16,/2022
  • what: While the ITS92 mAbs the authors report herein are not the first reported SIV gp41-specific nAbs , and display varying levels of strain-specific neutralizing activity against SIVsmE660 only, several ITS92 nAbs are notable for their ability to achieve near complete neutralization of SIVsmE660.CR54.2A5, a transmitted . . .

     

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