HIGHLIGHTS
- who: Katryn N. Furuya from the (UNIVERSITY) have published the research work: Bromocriptine Transcriptionally Activates the Multidrug Resistance Gene (pgp2/mdr1b) by a Novel Pathway*, in the Journal: (JOURNAL) of November/11,/1996
- what: This finding complements the studies shown in Table I by demonstrating that selective D2 dopamine receptor antagonists block bromocriptine activation of the pgp2/mdr1b promoter.
- future: Clearly the future studies with deletion constructs of the pgp2/mdr1b promoter will delineate the important ciselements and additional intracellular signals required for pgp2/mdr1b transcriptional activation by bromocriptine.
SUMMARY
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