Brønsted acid catalyzed remote c6 functionalization of 2,3-disubstituted indoles with β -ketoester

HIGHLIGHTS

  • who: September and colleagues from the Lanzhou University, China have published the research: Bru00f8nsted acid catalyzed remote C6 functionalization of 2,3-disubstituted indoles with u03b2 -ketoester, in the Journal: (JOURNAL)
  • how: Initially the authors examined this indole C6 functionalization reaction using u03b2u03b3-unsaturated u03b1-ketoester 1a and 23-dimethyl1H-indole 2a as model substrates. On the basis of these results and the previous literatures the authors proposed a plausible reaction model to illustrate the regioselectivity of this reaction. The authors declare that the research was conducted in the absence of any commercial or financial . . .

     

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