Brucella effectors nyxa and nyxb target senp3 to modulate the subcellular localisation of nucleolar proteins

HIGHLIGHTS

• who: Arthur Louche from the (UNIVERSITY) have published the research work: Brucella effectors NyxA and NyxB target SENP3 to modulate the subcellular localisation of nucleolar proteins, in the Journal: (JOURNAL) of 23/Dec/2022
• what: One of the main proteins identified was SENP3, and in view of its nuclear localisation and its diverse range of functions in key cellular processes and response to stress, the authors focused on this potential target. The authors report the identification of two Brucella effectors that target SENP3 and induce its delocalisation from the nucleoli during infection.
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