Brucella omp25 upregulates mir-155, mir-21-5p, and mir-23b to inhibit interleukin-12 production via modulation of programmed death-1 signaling in human monocyte/macrophages

HIGHLIGHTS

• who: Dewen Tong and Yong Huang from the Federal University of Pará, Brazil have published the research: Brucella Omp25 Upregulates miR-155, miR-21-5p, and miR-23b to Inhibit Interleukin-12 Production via Modulation of Programmed Death-1 Signaling in Human Monocyte/Macrophages, in the Journal: (JOURNAL)
• what: The authors evaluated the effects of Omp25 on the Toll-like receptor 4 and 7/8 agonist lipopolysaccharide (LPS)/ R848-induced IL-12 expression in monocyte/macrophages (M/MΦs). The authors have provided strong evidence for the roles of microRNAs (miR-155, -23b and -21 . . .
  

   

  

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