Brugada syndrome: from molecular mechanisms and genetics to risk stratification

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SUMMARY

    Clinical Characteristics and Diagnostic Criteria of BrS BrS is commonly diagnosed during the fifth decade of life, with an average age of 41 ± 15 years; however, it has also been reported in pediatric and geriatric patients. Although many asymptomatic individuals with a Brugada ECG are fortuitously discovered, a minority of patients with BrS experience symptoms, such as nocturnal agonal breathing, syncope, and/or palpitations, which may progress to ventricular arrhythmias or SCD. In a comprehensive study of 166 BrS patients who underwent exercise testing, ST-segment elevation was reported in 57% of individuals with . . .

     

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