Bufalin inhibits tumorigenesis, stemness, and epithelial-mesenchymal transition in colorectal cancer through a c-kit/slug signaling axis

HIGHLIGHTS

  • who: Ling Ding and colleagues from the Academy of Integrative Medicine, Fujian University of Traditional Chinese Medicine, Fuzhou, China have published the research: Bufalin Inhibits Tumorigenesis, Stemness, and Epithelial-Mesenchymal Transition in Colorectal Cancer through a C-Kit/Slug Signaling Axis, in the Journal: (JOURNAL) of 11/Oct/2022
  • what: Diethylaminobenzaldehyde (DEAB), which can inhibit the activity 5 of 19 of ALDH, was used as a negative control to obtain background readings. The authors used PDOs to further explore the efficacy of bufalin against CRC and the role of C-Kit/Slug signaling pathway. All . . .

     

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