Butyrate lowers cellular cholesterol through hdac inhibition and impaired srebp-2 signalling

HIGHLIGHTS

• who: Stephanie Bridgeman and collaborators from the Curtin Health Innovation Research Institute and Curtin Medical School, Curtin University, Bentley, WA, Australia have published the research work: Butyrate Lowers Cellular Cholesterol through HDAC Inhibition and Impaired SREBP-2 Signalling, in the Journal: (JOURNAL)
• what: This study compares the influence of butyrate and other to that of statins on cholesterol metabolism in multiple cell lines but primarily in HepG2 hepatic cells due to the importance of the liver in cholesterol metabolism.
• future: The authors cannot therefore rule out the possibility that the decrease in active . . .
  

   

  

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