Butyrate supplementation exacerbates myocardial and immune cell mitochondrial dysfunction in a rat model of faecal peritonitis

HIGHLIGHTS

  • who: Vera B. M. Peters and colleagues from the Bloomsbury Institute of Intensive Care Medicine, Division of Medicine, University College London, London WC E BT, UK have published the paper: Butyrate Supplementation Exacerbates Myocardial and Immune Cell Mitochondrial Dysfunction in a Rat Model of Faecal Peritonitis, in the Journal: (JOURNAL)
  • what: In the model the authors attempted to mimic a more realistic clinical scenario, with butyrate administration commenced at 6 h after the induction of sepsis when animals were manifesting clinical features, plus maintenance of an adequate volaemic status.
  • how: An overview is . . .

     

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