Bypassing the resistance mechanisms of the tumor ecosystem by targeting the endoplasmic reticulum stress pathway using ruthenium- and osmium-based organometallic compounds: an exciting long-term collaboration with dr. michel pfeffer

HIGHLIGHTS

  • who: Christian Gaiddon et al. from the (UNIVERSITY) have published the research: Bypassing the Resistance Mechanisms of the Tumor Ecosystem by Targeting the Endoplasmic Reticulum Stress Pathway Using Ruthenium- and Osmium-Based Organometallic Compounds: An Exciting Long-Term Collaboration with Dr. Michel Pfeffer, in the Journal: Molecules 2021, 26, 5386. of /2021/
  • what: The study had three important objectives: establish whether RDC11 had anticancer properties in_vivo using animal models; assess its toxicity on healthy cells and healthy tissues; identify the molecular mechanisms used by RDC11 for its cytotoxicity. Experience, the authors aimed to further develop . . .

     

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