HIGHLIGHTS
- who: Anika Alberts from the Institut have published the research: C-reactive protein (CRP) recognizes uric acid crystals and recruits proteases C1 and MASP1, in the Journal: Rheumatology, Hannover of 30/03/2020
- what: The authors show that CRP directly binds to MSU crystals with a similar binding strength and Ca2+-dependency as its synthetic ligand PC-agarose, which makes MSU crystals a suitable matrix for purification of CRP.
- how: The authors repeated the experiment with plasma from three distinct donors purified both MSU crystal- and PC-agarose-binding proteins and applied them . . .
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